Human motivation, a cornerstone of social sciences, is influenced by biological, psychological, and spiritual needs. This study explores the role of spiritual needs in human motivation theories, integrating Islamic perspectives with modern psychology. A theoretical and analytical review was conducted, drawing from 63 Islamic and psychological sources collected from databases like SID, Magiran, Google Scholar, and relevant books. Findings indicate that spiritual needs, rooted in human nature, are implicitly addressed in traditional theories such as Maslow’s hierarchy and Alderfer’s ERG model, while newer theories like Terror Management Theory and Piconus’s four-domain model explicitly incorporate them. Workplace spirituality enhances motivation, creativity, and organizational commitment, with spiritual intelligence serving as a key driver of intrinsic motivation. This study emphasizes the need to integrate spiritual needs into motivation theories to better understand human behavior. It recommends future research employ empirical approaches, such as longitudinal and mixed-methods studies, to examine the impact of spiritual needs across diverse populations and organizational contexts.